Collagen biostimulators: A comparative study between calcium hydroxyapatite x poly-l-lactic acid
DOI:
https://doi.org/10.52076/eacad-v6i2.647Keywords:
Collagen biostimulators; Calcium hydroxyapatite; Poly-l-lactic acid; Skin aging; Dermal fillers.Abstract
Collagen biostimulators emerged to increase collagen production, reduce volume loss, and smooth facial expressions caused by aging. They are injectable, absorbable products compatible with the human body, with the main function of stimulating the production of collagen in the treated area through microspheres. The purpose of this literature review is to provide some guidelines on CaHA and PLLA for facial rejuvenation. A literature review of collagen biostimulators based on Calcium Hydroxyapatite (Radiesseâ) and Poly-l-lactic acid (Sculptra®) was carried out, using the Pubmed, SciELO, Google scholar, Bireme platforms, in English and Portuguese as research bases. Articles from 2006 to 2024 were selected. The objective of this study is to present the efficacy of each one, discuss the techniques, efficacy, mechanisms of action, ideal application sites, contraindications and complications. We conclude that these agents have roles in skin rejuvenation, although they present risks and adverse effects such as hypersensitivity, bruising, pain, nodules and vascular involvement. Even though collagen biostimulators are excellent materials capable of preventing or reversing the effects of facial aging, there is not, however, a perfect dermal biostimulator, as all of them can generate adverse effects, and the professional must know how to select the ideal product for the treatment of each patient.
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